American Physicians and Surgeons (AAPS): Hydroxychloroquine 90% Effective on COVID-19

Written by Association of American Physicians and Surgeons (AAPS)

In a letter to Gov. Doug Ducey of Arizona, the Association of American Physicians and Surgeons (AAPS) presents a frequently updated table of studies that report results of treating COVID-19 with the anti-malaria drugs chloroquine (CQ) and hydroxychloroquine (HCQ, Plaquenil®).

To date, the total number of reported patients treated with HCQ, with or without zinc and the widely used antibiotic azithromycin, is 2,333, writes AAPS, in observational data from China, France, South Korea, Algeria, and the U.S. Of these, 2,137 or 91.6 percent improved clinically. There were 63 deaths, all but 11 in a single retrospective report from the Veterans Administration where the patients were severely ill.

The antiviral properties of these drugs have been studied since 2003. Particularly when combined with zinc, they hinder viral entry into cells and inhibit replication. They may also prevent overreaction by the immune system, which causes the cytokine storm responsible for much of the damage in severe cases, explains AAPS. HCQ is often very helpful in treating autoimmune diseases such as lupus and rheumatoid arthritis.

Additional benefits shown in some studies, AAPS states, is to decrease the number of days when a patient is contagious, reduce the need for ventilators, and shorten the time to clinical recovery.

Peer-reviewed studies published from January through April 20, 2020, provide clear and convincing evidence that HCQ may be beneficial in COVID-19, especially when used early, states AAPS. Unfortunately, although it is perfectly legal to prescribe drugs for new indications not on the label, the Food and Drug Administration (FDA) has said that CQ and HCQ should be used for COVID-19 only in hospitalized patients in the setting of a clinical study if available. Most states are making it difficult for physicians to prescribe or pharmacists to dispense these medications.

As the letter to Gov. Ducey notes, “Many nations, including Turkey and India, are protecting medical workers and contacts of infected persons prophylactically. According to, deaths per million persons from COVID-19 as of Apr 27 are 167 in the U.S., 33 in Turkey, and 0.6 in India.”

After Morocco and Algeria began using HCQ, a trend break and sharp reduction in their COVID-19 case fatality rate occurred.

Vaccines and results of randomized double-blind controlled trials of new drugs are at best months away. But patients are dying now, while affordable, long-used drugs would be available except for government restrictions, AAPS states.

The Association of American Physicians and Surgeons (AAPS) has represented physicians of all specialties in all states since 1943. The AAPS motto is omnia pro aegroto, meaning everything for the patient.

Contact: Jane M. Orient, M.D., (520) 323-3110,

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Comments (3)

  • Avatar



    I’m at a loss as to why many health services and government do not wish to provide chloroquine (CQ) and hydroxychloroquine (HCQ, Plaquenil®) with supplements of vitamin D, and zinc. So far many studies show that they are effective (and cheap) and has few bad side effect.
    “Many nations, including Turkey and India, are protecting medical workers and contacts of infected persons prophylactically. According to, deaths per million persons from COVID-19 as of Apr 27 are 167 in the U.S., 33 in Turkey, and 0.6 in India.”
    If it is found to help many people then all well and good, if this prophylactic measure helps only a minority of those who later are infected still little is lost as this is a cheap treatment.
    All-in-all I believe it is a measure worthy of taking a chance with – heads you win greatly, tails you loose very little!


  • Avatar



    I am puzzled by Dr. Fauci’s unwilliness to approve of this Hydroxychloroquine, azithromycin, and zinc protocol, but especially the Hydroxy – if there is really much of a heart problem with it, I wouldn’t think that many people would be taking it as a prophylactic. It makes no sense. They have had great success treating patients in the early stages of disease. Now Fauci is pushing another newer drug that is going to be more expensive and it appears he may have a connection. He may also have a conflict of interest for other reasons. It is refreshing that the AAPS is giving their endorsement.


  • Avatar

    Albert Elul


    There is nothing to be surprised about Dr. Fauci’s and other cronies’ unwillingness to approve the 5 cent a pill malaria drug Hydroxychloroquine to fight the Chinese Communist Party virus (CCPv).

    If the world gets to know that ALL corona viruses, that is, most of the yearly influenza pandemics are easily treatable with a cheap, harmless chemical, the base chemical of which (Quinine) forms part of the tonic water drink, then Big Pharma will lose most of its sales, and profits, that are pocketed every year from the sale of the influenza vaccines.

    As an over-sixty year old, I had been making it a point to have the flu-jab every year, but now I have second thoughts. If I lay my hands on a pack or two of Plaquenil or under whatever name it is sold in Europe, I will skip the flu jab and treat my influenza virus if it turns uncomfortable. Zinc and Azithromycin antibiotic makes it even more potent gains corona viruses.

    That HCQ is effective against influenza viruses had been known since 2005, but we were kept in the dark.


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