• Home
  • Current News
  • Scientists studying cancer stumble on ‘breakthrough’ in search for baldness cure

Scientists studying cancer stumble on ‘breakthrough’ in search for baldness cure

Written by Telegraph Reporters

A cream or ointment may soon cure baldness or stop hair turning grey, a new study suggests. The cells that makes hairs and turns it grey was accidentally discovered by US scientists as they explored how certain cancer tumours form. The breakthrough could one day identify possible treatments for balding and hair greying and also explain why we age.

Associate Professor of Dermatology Dr Lu Le at UT Southwestern Medical Centre said: “Although this project was started in an effort to understand how certain kinds of tumours form, we ended up learning why hair turns grey and discovering the identity of the cell that directly gives rise to hair.

“With this knowledge, we hope in the future to create a topical compound or to safely deliver the necessary gene to hair follicles to correct these cosmetic problems.”

The study found the protein called KROX20, more commonly associated with nerve development, turned on in skin cells that become the hair shaft. These hair precursor, or progenitor, cells then produce a protein called stem cell factor (SCF) which is essential for hair pigmentation. When scientists deleted the SCF gene in the hair progenitor cells in mice, their hair turned white. When they deleted the KROX20-producing cells, no hair grew and the mice became bald.

Prof Le made the discovery while studying a disorder called Neurofibromatosis Type 1, a rare genetic disease that causes tumours to grow on nerves.

Scientists already knew stem cells contained in a bulge area of hair follicles are involved in making hair and that SCF is important for pigmented cells. What they did not know in detail was what happens after those stem cells move down to the base, or bulb, of hair follicles and which cells in the hair follicles produce SCF – or that cells involved in hair shaft creation make the KROX20 protein.

If cells with functioning KROX20 and SCF are present, they move up from the bulb, interact with pigment-producing melanocyte cells, and grow into pigmented hairs. But without SCF, the hair in mouse models was grey, and then turned white with age, Without KROX20-producing cells, no hair grew.

Future research will try to find out if the KROX20 in cells and the SCF gene stop working properly as people age, leading to the greying and hair thinning seen in older people, as well as in male pattern baldness.

The research also could provide answers about why we age in general as hair greying and hair loss are among the first signs of ageing. The study was published in Genes & Development.

Read more at www.telegraph.co.uk

Trackback from your site.

Comments (1)

  • Avatar



    I want to specially thank Rick Simpson for saving my friend’s life
    with his healing oil. some years back my friend Jane was diagonized with
    a deadly disease cancer of the lungs, we try all medication all to no
    avail, we also try to do the oil our selves but we were doing more harm
    than worse. until an old friend of ours told Rose and tell her about RSO
    that cures cancer completely, she gave us the email address of Rick
    Simpson (ricksimpsoncannabisoil41@gmail.com)
    from that very moment we decided to give it a trier, by emailing Rick
    Simpson. instantly we got a reply from him asking us what

    the exact cancer problem that my friend Rose has, we explained every
    details of it to him, and he told us, that his oil will heal
    my friend cancer problem ..we did not buy the oil, we only paid for
    delivery charges.he told us that by the next 42hours or so the
    medication will get to our door step through the delivery services, we
    decided to give it a try and behold when we did, exactly 48hours of the
    medication came to our door step through the delivery agent and

    deliver it to us. immediately we emailed him that we have gotten the
    medication, and the usage instruction manual was also delivered to us.

    my friend Jane started the medication immediately just after a month of
    using RSO, Jane is now free from cancer problem, she is

    living a healthy life my utmost priority of sharing this short
    testimony is for those that are suffering from this kind of cancer

    diseases or if your friend or family members are suffering from this
    deadly disease, please don’t die in silence there is a cure
    for your cancer today don’t waste anytime further you have to email Rick
    Simpson directly and save your live and the lives of


Leave a comment